Wondering about leaky gut?
Harvard Health calls it a “medical mystery” and “mysterious ailment.” It’s been linked to everything from gut troubles, autoimmune diseases, and even mental health concerns.
I’m talking about “leaky gut” or “intestinal permeability”—have you heard of it?
Many doctors and the established medical community may not recognize it, but there is growing research to suggest it is associated with many health conditions.
What exactly is “leaky gut?” Do you have it? How does it happen? What can you do about it?
WHAT IS “LEAKY GUT”?
Your gut (gastrointestinal system) is not just a 30-foot-long muscular tube (tract) that starts at your mouth and ends with you going to the bathroom. In fact, it’s a vast and complex system with many functions. It breaks down food into smaller digestible bits, keeps it moving through the gastrointestinal tract, and skillfully absorbs water and nutrients while keeping out harmful substances. More and more research shows that these essential gut functions are interconnected throughout your body—to everything from your heart to your brain.
Your gastrointestinal tract is lined with millions of cells, all side-by-side in a single layer. In fact, this layer, if spread out flat, covers 400m2 of surface area! Those intestinal cells help the body to absorb what we need from foods and drinks, while keeping out what needs to stay out. It acts as a gatekeeper allowing in what your body uses, and keeping out the rest which ends up as waste. This ability to selectively allow some things in our gut to be absorbed while keeping others out is only possible if the cells are working properly and physically joined together very tightly. The bonds that keep the cells tightly together are called “tight junctions.”
Leaky gut happens when the tight junctions aren’t so tight anymore. The cellular barrier is irritated and weakened, allowing tiny holes to appear. These perforations allow things that normally would stay out of the bloodstream get into the bloodstream. Things like food particles, waste products, and bacteria.
When these get into the bloodstream your immune system is triggered to start fighting them. Similarly to how your immune system starts fighting the cold virus and causes inflammation. This immune reaction is normal and helps keep you healthy.
DO YOU HAVE LEAKY GUT?
The symptoms of leaky gut are similar to those of other digestive conditions like inflammatory bowel disease, celiac disease, and Crohn's disease. Symptoms can include:
Diarrhea
Constipation
Cramps
Bloating
Food Sensitivities
Nutrient Deficiencies
But, because the food particles, toxins, and bacteria have been absorbed into the bloodstream which travels throughout your body, symptoms can appear anywhere. Studies show that leaky gut may feel like:
Fatigue
Headeaches
Confusion
Difficulty concentrating
Join pain
Skin problems (e.g. acne, rashes, eczema)
Leaky gut is also linked with:
Diabetes
Polycystic Ovarian Syndrome (PCOS)
Liver Disease
Chronic Fatigue Syndrome
Autoimmune Diseases (like lupus and multiple sclerosis)
Anxiety and depression
And more
Many of these gut and non-gut symptoms and conditions are linked to chronic inflammation, but more research is needed to understand how they are connected.
Even if you have some of these symptoms, the fact is, it’s very difficult to diagnose a leaky gut, nor how leaky it is. This means that, while there are some biomarker tests, there isn’t a reliable diagnostic test available just yet. So, it’s difficult to say whether your symptoms are from leaky gut, or whether leaky gut is a symptom of another issue.
WHAT CAUSES LEAKY GUT
It’s not 100 percent clear what causes those bonds to loosen and result in tiny perforations in the gut barrier. In fact, we’re just starting to understand how the gut barrier functions and there is a lot of ongoing research.
Part of leaky gut may be due to the genes you inherit from your parents. It can also be from medications or gut infections. Leaky gut is also linked to eating a diet that is low in gut-friendly fiber (adults should aim for 35+g of fiber per day). It can also be from consuming too much added sugar and saturated fat. Leaky gut may even result from stress or an imbalance in the diversity and numbers of your friendly gut microbes. Nutrient deficiencies, GMO foods, processed foods, and a diet higher in offending foods can lead to a leaky gut.
Also, as you age your cells can get damaged more easily and heal slowly, including the cells that line your gut. This can leave you more susceptible to loosening of the gut barrier.
WHAT CAN YOU DO ABOUT LEAKY GUT?
One way to approach a suspected leaky gut is to address inflammation and eat a more gut-friendly diet. This means reducing excessive alcohol and processed foods that tend to be high in fat and sugar or artificial sweeteners. It’s also a good idea to avoid foods that your allergic or sensitive to. For example, if you have diagnosed celiac disease, you want to be sure to stay away from gluten, as exposing your gut to it can cause a large inflammatory response.
One way of pinpointing specific trigger/sensitive foods is by taking a blood test called MRT/LEAP. This test helps pinpoint the most reactive foods (out of 170 different foods) and the least reactive foods for you through immune mediators in the blood. Once your test has been processed, you come up with a tailored food plan and reintroduction schedule that helps lower inflammation in your body, heal your gut, and pinpoint the exact foods causing your symptoms. If you’re interested in learning more and scheduling a consultation about this, contact me HERE as I’m a certified MRT/LEAP practitioner.
Another great way to test if you have leaky gut is by measuring zonulin levels. This can be done via a blood test or through a Comprehensive Stool Analysis test (another great test to see how your gut is doing). Zonulin is a protein that increases the permeability of the tight junctions between the cell walls of your digestive tract. I am also able to order these tests for clients (except in certain states, like NY, NJ for example).
Enjoying more foods rich in gut-friendly probiotics and fiber, which is a prebiotic (food for the friendly gut microbes). These include:
Yogurt or kefir (make sure that you’re buying high quality yogurt without added sugars - opt for plain and minimal ingredients like Fage for example)
Fermented foods (e.g. kimchi, sauerkraut, miso, refrigerated pickles, etc.)
Kombucha (again, look for higher quality with minimal ingredients and lower added sugars)
Fruits and vegetables (e.g. berries, oranges, broccoli, carrots, zucchini, artichoke, asparagus, avocados)
Nuts and seeds (e.g., walnuts, cashews, chia seeds, flax seeds, pumpkin seeds, almonds, etc.)
Whole grains (if tolerated - these can contribute to leaky gut as well, but for those who CAN tolerate them, small amounts of 100% whole wheat, quinoa, etc.)
Chicory root “coffee” substitutes or Coffee alternatives that utilize lion’s mane and reishi mushrooms
Quality/homemade bone broth (incredibly gut-healing)
Supplements may be necessary for some - like L-glutamine, probiotics (with specific beneficial strains), digestive enzymes, licorice root, marshmallow root, collagen or gelatin powder, NAG (N-acetyl glucosamine), shilajit, reishi mushrooms, lion’s mane mushrooms) - these recommendations are based on the individual
Pro Tip: If you’re going to proactively increase your fiber intake, do it over several days or weeks because sudden increases in fiber can cause gas, bloating, and other gut discomfort. If you have IBS, talk to your doctor, or me (CLICK HERE) to see if certain fibers may worsen your condition and which are recommended.
Also, regular exercise can help your digestive system. This means taking even a 15- or 20-minute walk after you eat to help you digest your food. And don’t forget the importance of stress management, quality sleep, and not smoking.
Pro Tip: before eating a meal, give gratitude/say a prayer, and take 1 minute to focus on your breath. Breathe in deeply for a count of 4, hold for a count of 4, breath out for a count of 4, hold for a count of 4 and repeat for 1 minute.
Calming the body before eating allows for less tension and therefore less stress on the digestive system. Eating while relaxed will help slow you down, chew more thoroughly, and not be in a heightened “fight or flight” state. This allows the digestive system to do what it needs to do easier and you’ll absorb your nutrients better!
If you plan on making changes to your diet and lifestyle, consider keeping a journal to help see if the changes are helping your symptoms.
FINAL THOUGHTS
A few simple shifts toward a gut-friendly diet can help you navigate leaky gut.
A leaky gut is associated with gut and non-gut symptoms. It’s an inflammatory condition that has been linked to metabolic disorders, autoimmune conditions, and even mental health. There is no good diagnostic test at this time to know for sure if you have it or not. And remember, this is still a rather new area of research, so more information emerges all the time.
In the meantime, if you have symptoms that suggest a leaky gut, you can move toward a more gut-friendly diet. Try cutting down on alcohol, processed foods, and any that you may be allergic or sensitive to. Replace these foods and drinks with ones higher in gut-friendy probiotics and fiber. And remember that regular exercise, stress management, and quality sleep are great lifestyle strategies for your gut and the rest of your body.
If leaky gut or other inflammatory symptoms are bothering you, book a free discovery call with me to see if my services can help you. To schedule, CLICK HERE.
REFERENCES
Harvard Health. (2018). Putting a stop to leaky gut. Retrieved from
https://www.health.harvard.edu/blog/putting-a-stop-to-leaky-gut-2018111815289
Harvard Health. (2018). Putting a stop to leaky gut: What can you do about this mysterious ailment? Retrieved from
https://www.health.harvard.edu/diseases-and-conditions/putting-a-stop-to-leaky-gut
Leech, B., Schloss, J. & Steel, J. (2019). Association between increased intestinal permeability and disease: A systematic review. Advances in Integrative Medicine. 6(1), 23-34. https://doi.org/10.1016/j.aimed.2018.08.003
https://www.sciencedirect.com/science/article/pii/S221295881730160X
Mayo Clinic. (2016). Food sensitivities may affect gut barrier function. Retrieved from
Medical News Today. (2019). What to know about leaky gut syndrome. Retrieved from
https://www.medicalnewstoday.com/articles/326117.php
Medical News Today. (2019). What is the best diet for leaky gut syndrome? Retrieved from https://www.medicalnewstoday.com/articles/326102.php
Medscape. (2019). Is 'Leaky Gut' the Root of All Ills? Retrieved from
https://www.medscape.com/viewarticle/913237
Mu, Q., Kirby, J., Reilly, C. M., & Luo, X. M. (2017). Leaky Gut As a Danger Signal for Autoimmune Diseases. Frontiers in immunology, 8, 598. doi:10.3389/fimmu.2017.00598
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440529/
National Institutes of Health News in Health. (2017, May). Keeping Your Gut in Check. Retrieved from https://newsinhealth.nih.gov/2017/05/keeping-your-gut-check
Obrenovich M. (2018). Leaky Gut, Leaky Brain? Microorganisms, 6(4), 107. doi:10.3390/microorganisms6040107
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313445/
US Department of Health and Human Services and US Department of Agriculture. (2015). Dietary Guidelines for Americans 2015-2020, eighth edition. Appendix 7. Nutritional Goals for Age-Sex Groups Based on Dietary Reference Intakes and Dietary Guidelines Recommendations. Retrieved from
https://health.gov/dietaryguidelines/2015/guidelines/appendix-7/
